FGF5, fibroblast growth factor 5

FGF5, fibroblast growth factor 5

• The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

• Gene Synonyms (HBGF-5, Smag-82, TCMGLY, fibroblast growth factor 5, heparin-binding growth factor 5,)
• NCBI Gene ID: 2250
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8NBG6
  UNIPROT ID#>>P12034
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

fibroblast growth factor 5 interacts with:

• fibroblast growth factor receptor 1
  fibroblast growth factor receptor 2
  fibroblast growth factor receptor 3
  fibroblast growth factor receptor 4
  mitogen-activated protein kinase 1
  pentraxin 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.