STAB1, stabilin 1

STAB1, stabilin 1

• This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CLEVER-1, FEEL-1, FELE-1, FEX1, SCARH2, STAB-1, stabilin-1, MS-1 antigen, common lymphatic endothelial and vascular endothelial receptor-1, fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger receptor-1, fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1,)
• NCBI Gene ID: 23166
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NY15
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

stabilin 1 interacts with:

• chitinase domain containing 1
  golgi associated, gamma adaptin ear containing, ARF binding protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.