FZD2, frizzled class receptor 2

FZD2, frizzled class receptor 2

• This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways. [provided by RefSeq, Dec 2010]

• Gene Synonyms (Fz2, OMOD2, fz-2, fzE2, hFz2, frizzled-2, frizzled 2, seven transmembrane spanning receptor, frizzled family receptor 2, frizzled homolog 2,)
• NCBI Gene ID: 2535
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86UZ8
  UNIPROT ID#>>Q14332
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

frizzled class receptor 2 interacts with:

• 5-hydroxytryptamine receptor 3C
  adhesion G protein-coupled receptor G5
  ETAA1 activator of ATR kinase
  family with sequence similarity 189 member A2
  G protein-coupled receptor 21
  G protein-coupled receptor 52
  gamma-aminobutyric acid type A receptor subunit epsilon
  LY6/PLAUR domain containing 6
  lysosomal associated membrane protein 1
  metallophosphoesterase 1
  neuritin 1
  prostaglandin I2 receptor
  receptor tyrosine kinase like orphan receptor 2
  solute carrier family 39 member 4
  spectrin repeat containing nuclear envelope family member 4
  transmembrane serine protease 11B
  transmembrane serine protease 12
  uroplakin 1A
  Wnt family member 3A
  Wnt family member 5A
  zinc activated ion channel

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.