GABBR1, gamma-aminobutyric acid type B receptor subunit 1

GABBR1, gamma-aminobutyric acid type B receptor subunit 1

• This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jan 2016]

• Gene Synonyms (GABABR1, GABBR1-3, GB1, GPRC3A, gamma-aminobutyric acid type B receptor subunit 1, GABA-B receptor, R1 subunit, gamma-aminobutyric acid (GABA) B receptor, 1, seven transmembrane helix receptor,)
• NCBI Gene ID: 2550
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q59HG8
  UNIPROT ID#>>A0A1U9X7R0
  UNIPROT ID#>>Q9UBS5
  UNIPROT ID#>>Q5SUJ9
  UNIPROT ID#>>Q8IW08
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

gamma-aminobutyric acid type B receptor subunit 1 interacts with:

• activating transcription factor 5
  checkpoint with forkhead and ring finger domains
  cytoplasmic polyadenylation element binding protein 2
  G protein subunit alpha o1
  G protein subunit beta 1
  G protein subunit gamma 2
  gamma-aminobutyric acid type B receptor subunit 2
  janus kinase and microtubule interacting protein 1
  MYC associated factor X
  N-ethylmaleimide sensitive factor, vesicle fusing ATPase
  potassium channel tetramerization domain containing 16
  potassium inwardly rectifying channel subfamily J member 3
  potassium inwardly rectifying channel subfamily J member 6
  regulator of G protein signaling 4
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
  ubiquitin specific peptidase 14

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.