RAB3GAP2, RAB3 GTPase activating non-catalytic protein subunit 2

RAB3GAP2, RAB3 GTPase activating non-catalytic protein subunit 2

• The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.[provided by RefSeq, Oct 2009]

• Gene Synonyms (rab3 GTPase-activating protein non-catalytic subunit, RAB3 GTPase activating protein subunit 2 (non-catalytic), RGAP-iso, rab3 GTPase-activating protein 150 kDa subunit, rab3-GAP p150, rab3-GAP regulatory subunit, RAB3-GAP150, RAB3GAP150, SPG69, WARBM2, p150,)
• NCBI Gene ID: 25782
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H2M9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RAB3 GTPase activating non-catalytic protein subunit 2 interacts with:

• exosome component 6
  limb development membrane protein 1 like
  microtubule associated protein 1 light chain 3 alpha
  nucleoporin 43
  OTU deubiquitinase with linear linkage specificity like
  pleckstrin homology domain containing A4
  rhomboid domain containing 1
  RNA binding motif protein 26
  SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
  synoviolin 1
  testin LIM domain protein
  tRNA splicing endonuclease subunit 34
  UTP20 small subunit processome component

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.