GATA2, GATA binding protein 2

GATA2, GATA binding protein 2

• This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

• Gene Synonyms (DCML, IMD21, MONOMAC, NFE1B, endothelial transcription factor GATA-2,)
• NCBI Gene ID: 2624
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P23769
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

GATA binding protein 2 interacts with:

• ADAMTS like 4
  cullin 1
  cysteine rich tail 1
  F-box and WD repeat domain containing 7
  golgin A2
  H4 clustered histone 1
  hematopoietically expressed homeobox
  histone deacetylase 3
  histone deacetylase 5
  inosine monophosphate dehydrogenase 1
  Jun proto-oncogene, AP-1 transcription factor subunit
  keratin 40
  keratin associated protein 10-3
  keratin associated protein 10-9
  keratin associated protein 11-1
  keratin associated protein 13-3
  keratin associated protein 21-2
  keratin associated protein 3-1
  keratin associated protein 6-3
  keratin associated protein 7-1
  keratin associated protein 8-1
  LIM domain only 2
  lysine acetyltransferase 2A
  mediator complex subunit 1
  mitogen-activated protein kinase 1
  msh homeobox 2
  MyoD family inhibitor
  notch 2 N-terminal like A
  nuclear receptor subfamily 2 group C member 2
  PML nuclear body scaffold
  POU class 1 homeobox 1
  POU class 2 homeobox associating factor 1
  proline rich 20A
  proteasome 20S subunit alpha 3
  retinoic acid receptor alpha
  retinoid X receptor alpha
  ring-box 1
  RNA binding protein, mRNA processing factor
  signal transducer and activator of transcription 3
  SMAD family member 4
  S-phase kinase associated protein 1
  Spi-1 proto-oncogene
  TAL bHLH transcription factor 1, erythroid differentiation factor
  TNF receptor associated factor 1
  TNFAIP3 interacting protein 2
  trafficking protein particle complex 10
  trafficking protein particle complex 4
  trafficking protein particle complex 9
  zinc finger and BTB domain containing 16
  zinc finger and BTB domain containing 32
  zinc finger containing ubiquitin peptidase 1
  zinc finger protein, FOG family member 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.