ERAL1, Era like 12S mitochondrial rRNA chaperone 1

ERAL1, Era like 12S mitochondrial rRNA chaperone 1

• The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

• Gene Synonyms (GTPase Era, mitochondrial, ERA-like protein 1, Era G-protein-like 1, GTP-binding protein era homolog, GTPase, human homolog of E. coli essential cell cycle protein Era, conserved ERA-like GTPase, era (E. coli G-protein homolog)-like 1, CEGA, ERA, ERA-W, ERAL1A, ERAL1B, H-ERA, HERA-A, HERA-B, PRLTS6,)
• NCBI Gene ID: 26284
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75616
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Era like 12S mitochondrial rRNA chaperone 1 interacts with:

• 5'-nucleotidase, cytosolic IIIA
  acyl-CoA dehydrogenase family member 9
  ankyrin repeat and FYVE domain containing 1
  ATP synthase mitochondrial F1 complex assembly factor 1
  aurora kinase A interacting protein 1
  bromodomain containing 7
  CDGSH iron sulfur domain 3
  centrosomal protein 44
  coenzyme Q8B
  coenzyme Q9
  coiled-coil domain containing 8
  cullin associated and neddylation dissociated 1
  cytochrome c oxidase assembly factor COX14
  developmental pluripotency-associated 3
  malonyl-CoA-acyl carrier protein transacylase
  matrix AAA peptidase interacting protein 1
  methylphosphate capping enzyme
  mitochondrial ribosomal protein S2
  mitochondrial rRNA methyltransferase 1
  pleckstrin homology domain containing A4
  receptor interacting serine/threonine kinase 4
  solute carrier family 25 member 46
  spindle apparatus coiled-coil protein 1
  SSX family member 2 interacting protein
  tRNA methyltransferase 61B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.