DKK2, dickkopf WNT signaling pathway inhibitor 2

DKK2, dickkopf WNT signaling pathway inhibitor 2

• This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008]

• Gene Synonyms (dickkopf-related protein 2, dickkopf 2 homolog, dickkopf homolog 2, dickkopf-2, hDkk-2, DKK-2,)
• NCBI Gene ID: 27123
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UBU2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dickkopf WNT signaling pathway inhibitor 2 interacts with:

• keratin associated protein 10-6

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