- Gene Overview
- Interaction Network
- Sequence Verification
PCDH11X, protocadherin 11 X-linked
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This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
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Gene Synonyms (protocadherin-11 X-linked, Protocadherin on the Y chromosome, Protocadherin prostate cancer, Protocadherin-11 Y-linked, Protocadherin-22, Protocadherin-PC, protein phosphatase 1, regulatory subunit 119, protocadherin 11X, protocadherin on the X chromosome, protocadherin-S, PCDH-X, PCDH-Y, PCDH11, PCDH11Y, PCDH22, PCDHX, PPP1R119,)
- NCBI Gene ID:
27328
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q9BZA7
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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protocadherin 11 X-linked interacts with:
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