GP9, glycoprotein IX platelet

GP9, glycoprotein IX platelet

• This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008]

• Gene Synonyms (platelet glycoprotein IX, glycoprotein 9, CD42a, GPIX,)
• NCBI Gene ID: 2815
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P14770
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glycoprotein IX platelet interacts with:

• amyloid beta precursor protein binding protein 2
  homeobox A1
  homeobox A1
  sprouty RTK signaling antagonist 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.