HPCA, hippocalcin

HPCA, hippocalcin

• The protein encoded by this gene is a member of neuron-specific calcium-binding proteins family found in the retina and brain. This protein is associated with the plasma membrane. It has similarities to proteins located in the photoreceptor cells that regulate photosignal transduction in a calcium-sensitive manner. This protein displays recoverin activity and a calcium-dependent inhibition of rhodopsin kinase. It is identical to the rat and mouse hippocalcin proteins and thought to play an important role in neurons of the central nervous system in a number of species. [provided by RefSeq, Jul 2008]

• Gene Synonyms (neuron-specific calcium-binding protein hippocalcin, calcium-binding protein BDR-2, dystonia 2, torsion (autosomal recessive), BDR2, DYT2,)
• NCBI Gene ID: 3208
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P84074
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

hippocalcin interacts with:

• C1q and TNF related 2
  creatine kinase, mitochondrial 1A
  deltex E3 ubiquitin ligase 2
  dynein axonemal assembly factor 2
  GATA binding protein 5
  HCLS1 associated protein X-1
  interleukin 36 receptor antagonist
  mitogen-activated protein kinase kinase kinase 10
  MLLT10 histone lysine methyltransferase DOT1L cofactor
  myeloid derived growth factor
  NLR family apoptosis inhibitory protein
  N-myristoyltransferase 1
  nuclear FMR1 interacting protein 1
  proline rich 35
  solute carrier family 16 member 3
  TEPSIN adaptor related protein complex 4 accessory protein
  tumor protein p53
  ubiquinol-cytochrome c reductase binding protein
  von Willebrand factor C domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.