- Gene Overview
- Interaction Network
- Sequence Verification
NLRP14, NLR family pyrin domain containing 14
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The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]
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Gene Synonyms (CLR11.2, GC-LRR, NALP14, NOD5, PAN8, NACHT, LRR and PYD domains-containing protein 14, NACHT, LRR and PYD containing protein 14, NACHT, leucine rich repeat and PYD containing 14, nucleotide-binding oligomerization domain protein 5, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 14,)
- NCBI Gene ID:
338323
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q86W24
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
NLR family pyrin domain containing 14 interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
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