IL11RA, interleukin 11 receptor subunit alpha

IL11RA, interleukin 11 receptor subunit alpha

• Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

• Gene Synonyms (interleukin-11 receptor subunit alpha, IL-11 receptor subunit alpha, IL-11R subunit alpha, interleukin 11 receptor, alpha, interleukin-11 receptor alpha chain, CRSDA,)
• NCBI Gene ID: 3590
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5VZ79
  UNIPROT ID#>>Q14626
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

interleukin 11 receptor subunit alpha interacts with:

• olfactomedin 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.