- Gene Overview
- Interaction Network
- Sequence Verification
KCNH1, potassium voltage-gated channel subfamily H member 1
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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
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Gene Synonyms (EAG, EAG1, Kv10.1, TMBTS, ZLS1, h-eag, hEAG, hEAG1, potassium voltage-gated channel subfamily H member 1, EAG channel 1, ether-a-go-go 1, ether-a-go-go potassium channel 1, ether-a-go-go, Drosophila, homolog of, potassium channel, voltage gated eag related subfamily H, member 1, potassium voltage-gated channel, subfamily H (eag-related), member 1, voltage-gated potassium channel subunit Kv10.1,)
- NCBI Gene ID:
3756
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>O95259
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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potassium voltage-gated channel subfamily H member 1 interacts with:
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