- Gene Overview
- Interaction Network
- Sequence Verification
MMP16, matrix metallopeptidase 16
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq, Oct 2010]
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Gene Synonyms (C8orf57, MMP-X2, MT-MMP2, MT-MMP3, MT3-MMP, matrix metalloproteinase-16, MMP-16, MT-MMP 3, MT3MMP, MTMMP3, Putative transmembrane protein C8orf57, matrix metallopeptidase 16 (membrane-inserted), membrane-type matrix metalloproteinase 3, membrane-type-3 matrix metalloproteinase,)
- NCBI Gene ID:
4325
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>P51512
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
matrix metallopeptidase 16 interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
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