NTHL1, nth like DNA glycosylase 1

NTHL1, nth like DNA glycosylase 1

• The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity. [provided by RefSeq, Oct 2008]

• Gene Synonyms (FAP3, NTH1, OCTS3, hNTH1, endonuclease III-like protein 1, DNA glycoslyase/AP lyase, DNA glycosylase/AP lyase, bifunctional DNA N-glycoslyase/DNA-(apurinic or apyrimidinic site) lyase, bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase, nth endonuclease III-like 1,)
• NCBI Gene ID: 4913
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P78549
  UNIPROT ID#>>E5KTI5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nth like DNA glycosylase 1 interacts with:

• calcium/calmodulin dependent protein kinase kinase 1
  cytosolic iron-sulfur assembly component 2B
  G1 to S phase transition 1
  glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
  H4 clustered histone 1
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  MINDY lysine 48 deubiquitinase 3
  mitochondrial rRNA methyltransferase 3
  MMS19 homolog, cytosolic iron-sulfur assembly component
  nuclear RNA export factor 1
  pleckstrin homology domain containing A4
  proliferating cell nuclear antigen
  replication protein A1
  replication protein A2
  replication protein A3
  ribosomal protein L10
  ribosomal protein L35
  SRSF protein kinase 2
  tumor protein p53
  zinc finger CCCH-type containing, antiviral 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.