GPR143, G protein-coupled receptor 143

GPR143, G protein-coupled receptor 143

• This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y. [provided by RefSeq, Dec 2009]

• Gene Synonyms (NYS6, OA1, G-protein coupled receptor 143, ocular albinism 1, ocular albinism type 1 protein,)
• NCBI Gene ID: 4935
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P51810
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

G protein-coupled receptor 143 interacts with:

• succinate-CoA ligase GDP-forming subunit beta

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.