- Gene Overview
- Interaction Network
- Sequence Verification
OLR1, oxidized low density lipoprotein receptor 1
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This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
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Gene Synonyms (CLEC8A, LOX1, LOXIN, SCARE1, SLOX1, oxidized low-density lipoprotein receptor 1, C-type lectin domain family 8 member A, hLOX-1, lectin-type oxidized LDL receptor 1, ox LDL receptor 1, oxidized low density lipoprotein (lectin-like) receptor 1, oxidized low-density lipoprotein receptor 1, soluble form, scavenger receptor class E, member 1,)
- NCBI Gene ID:
4973
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>P78380
UNIPROT ID#>>A0A024RAU0
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for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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oxidized low density lipoprotein receptor 1 interacts with:
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