MPP6, membrane palmitoylated protein 6

MPP6, membrane palmitoylated protein 6

• Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (MAGUK p55 subfamily member 6, MAGUK protein p55T, VELI-associated MAGUK 1, membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6), protein associated with Lin7 2, PALS2, VAM-1, VAM1, p55T,)
• NCBI Gene ID: 51678
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RA25
  UNIPROT ID#>>Q9NZW5
  UNIPROT ID#>>B8ZZG1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

membrane palmitoylated protein 6 interacts with:

• dynein light chain roadblock-type 1
  egl-9 family hypoxia inducible factor 3
  exosome component 4
  exosome component 5
  exosome component 6
  kinetochore localized astrin (SPAG5) binding protein
  lin-7 homolog B, crumbs cell polarity complex component
  lin-7 homolog C, crumbs cell polarity complex component
  MINDY lysine 48 deubiquitinase 3
  NOP2/Sun RNA methyltransferase 2
  purinergic receptor P2Y12
  Rho GTPase activating protein 18
  TAFA chemokine like family member 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.