SERPINB9, serpin family B member 9

SERPINB9, serpin family B member 9

• This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2012]

• Gene Synonyms (serpin B9, cytoplasmic antiproteinase 3, peptidase inhibitor 9, protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9, testicular tissue protein Li 180, CAP-3, CAP3, PI-9, PI9,)
• NCBI Gene ID: 5272
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P50453
  UNIPROT ID#>>A0A024QZT4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

serpin family B member 9 interacts with:

• bromodomain containing 7
  coiled-coil domain containing 90B
  COP9 signalosome subunit 6
  ergosterol biosynthesis 28 homolog
  immunoglobin superfamily member 21
  immunoglobulin superfamily member 8
  ligand dependent nuclear receptor interacting factor 1
  mediator complex subunit 31
  pleckstrin homology and RUN domain containing M1
  pre-mRNA processing factor 40 homolog A
  RNA binding motif protein 48
  SET domain bifurcated histone lysine methyltransferase 1
  testis expressed 101
  TLE family member 1, transcriptional corepressor
  TNF receptor associated factor 5
  tubulin beta 2A class IIa
  tumor protein p53
  ubiquitin protein ligase E3 component n-recognin 1
  unc-119 lipid binding chaperone
  VAMP associated protein A
  zinc fingers and homeoboxes 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.