LPCAT2, lysophosphatidylcholine acyltransferase 2

LPCAT2, lysophosphatidylcholine acyltransferase 2

• This gene encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine. The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The enzyme may localize to the endoplasmic reticulum and the Golgi. [provided by RefSeq, Feb 2009]

• Gene Synonyms (lysophosphatidylcholine acyltransferase 2, 1-AGP acyltransferase 11, 1-AGPAT 11, 1-acylglycerol-3-phosphate O-acyltransferase 11, 1-acylglycerophosphocholine O-acyltransferase, 1-alkenylglycerophosphocholine O-acyltransferase, 1-alkylglycerophosphocholine O-acetyltransferase, LPAAT-alpha, LPC acyltransferase 2, LPCAT-2, acetyl-CoA:lyso-PAF acetyltransferase, acetyl-CoA:lyso-platelet-activating factor acetyltransferase, acyl-CoA:lysophosphatidylcholine acyltransferase 2, acyltransferase-like 1, lyso-PAF acetyltransferase, lyso-platelet-activating factor (PAF) acetyltransferase, lysoPC acyltransferase 2, lysophosphatidic acid acyltransferase alpha, AGPAT11, AYTL1, LysoPAFAT,)
• NCBI Gene ID: 54947
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7L5N7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

lysophosphatidylcholine acyltransferase 2 interacts with:

• hydroxysteroid 17-beta dehydrogenase 13
  limb development membrane protein 1 like
  major facilitator superfamily domain containing 14B
  pleckstrin homology domain containing A4
  reticulophagy regulator family member 3
  rhomboid domain containing 1
  transmembrane protein 25

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.