TMPRSS4, transmembrane serine protease 4

TMPRSS4, transmembrane serine protease 4

• This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CAPH2, MT-SP2, TMPRSS3, transmembrane protease serine 4, channel-activating protease 2, membrane-type serine protease 2, transmembrane protease, serine 4, transmembrane serine protease 3, type II membrane serine protease,)
• NCBI Gene ID: 56649
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7Z458
  UNIPROT ID#>>B7Z8X1
  UNIPROT ID#>>B7Z900
  UNIPROT ID#>>Q9NRS4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transmembrane serine protease 4 interacts with:

• C-type lectin domain containing 7A
  endogenous retrovirus group FRD member 1, envelope
  family with sequence similarity 209 member A
  fibronectin type III domain containing 9
  glutathione peroxidase 8 (putative)
  KASH domain containing 5
  RAS guanyl releasing protein 4
  sialic acid binding Ig like lectin 12
  spectrin repeat containing nuclear envelope family member 4
  sushi domain containing 3
  transmembrane protein 79

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.