RBAK, RB associated KRAB zinc finger

RBAK, RB associated KRAB zinc finger

• This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011]

• Gene Synonyms (ZNF769, RB-associated KRAB zinc finger protein, RB-associated KRAB repressor, zinc finger protein 769,)
• NCBI Gene ID: 57786
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NYW8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RB associated KRAB zinc finger interacts with:

• calcium and integrin binding family member 3
  calcium release activated channel regulator 2A
  caspase recruitment domain family member 9
  eukaryotic translation initiation factor 1A domain containing
  L3MBTL histone methyl-lysine binding protein 2
  ligand of numb-protein X 1
  sodium channel modifier 1
  testis specific 10
  tripartite motif containing 41
  zinc finger protein 169
  zinc finger protein 324B
  zinc finger protein 550
  zinc finger protein 648
  zinc finger protein 707
  zinc finger protein 785

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.