SEMA3F, semaphorin 3F

SEMA3F, semaphorin 3F

• This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin loop and a C-terminal basic domain. This gene is expressed by the endothelial cells where it was found to act in an autocrine fashion to induce apoptosis, inhibit cell proliferation and survival, and function as an anti-tumorigenic agent. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

• Gene Synonyms (semaphorin-3F, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 3F, semaphorin III/F, semaphorin IV, SEMA-IV, SEMA4, SEMAK,)
• NCBI Gene ID: 6405
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q59G50
  UNIPROT ID#>>Q13275
  UNIPROT ID#>>C9JPG5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

semaphorin 3F interacts with:

• neuropilin 1
  neuropilin 1
  neuropilin 2
  nuclear RNA export factor 1
  sex hormone binding globulin
  solute carrier family 35 member G2
  ubiquitin C
  ubiquitin like modifier activating enzyme 1
  vascular endothelial growth factor A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.