SOX12, SRY-box transcription factor 12

SOX12, SRY-box transcription factor 12

• Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. [provided by RefSeq, Jan 2013]

• Gene Synonyms (transcription factor SOX-12, SOX-22 protein, SRY (sex determining region Y)-box 12, SRY-box 12, SRY-related HMG-box gene 22, SOX22,)
• NCBI Gene ID: 6666
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O15370
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SRY-box transcription factor 12 interacts with:

• spermidine synthase

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