SRPRA, SRP receptor subunit alpha

SRPRA, SRP receptor subunit alpha

• The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

• Gene Synonyms (signal recognition particle receptor subunit alpha, DP-alpha, SR-alpha, SRP receptor alpha subunit, SRP-alpha, docking protein alpha, signal recognition particle receptor (docking protein), DP, SRPR, Sralpha,)
• NCBI Gene ID: 6734
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P08240
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SRP receptor subunit alpha interacts with:

• argonaute RISC catalytic component 2
  Bet1 golgi vesicular membrane trafficking protein
  bromodomain containing 7
  clusterin associated protein 1
  coiled-coil domain containing 61
  cytochrome c oxidase assembly factor COX14
  DDRGK domain containing 1
  dual specificity phosphatase 22
  elongation factor Tu GTP binding domain containing 2
  ER degradation enhancing alpha-mannosidase like protein 3
  EvC ciliary complex subunit 2
  H4 clustered histone 1
  integrator complex subunit 14
  interleukin 27 receptor subunit alpha
  IQ motif and Sec7 domain ArfGEF 1
  jun B proto-oncogene
  katanin catalytic subunit A1
  KIAA2013
  limb development membrane protein 1 like
  N-alpha-acetyltransferase 15, NatA auxiliary subunit
  nuclear receptor subfamily 2 group C member 2
  OTU deubiquitinase with linear linkage specificity like
  peptide deformylase, mitochondrial
  pleckstrin homology domain containing A4
  protein phosphatase 6 regulatory subunit 1
  receptor interacting serine/threonine kinase 4
  rhomboid 5 homolog 2
  rhomboid domain containing 1
  ribosomal protein L35
  ring finger protein 123
  ring finger protein 213
  RUN and SH3 domain containing 2
  sequestosome 1
  serine protease 23
  signal sequence receptor subunit 2
  solute carrier family 39 member 12
  solute carrier family 39 member 9
  spindle and centriole associated protein 1
  SRP receptor subunit beta
  synoviolin 1
  TARBP2 subunit of RISC loading complex
  tectonic family member 2
  tectonic family member 3
  trans-golgi network protein 2
  transient receptor potential cation channel subfamily C member 4 associated protein
  transmembrane phosphatase with tensin homology
  transmembrane protein 17
  transmembrane protein 216
  transmembrane protein 237
  transmembrane protein 67
  tubulin alpha 1a
  ubiquilin 2
  ubiquitin like 4A
  vir like m6A methyltransferase associated
  WW domain containing oxidoreductase
  zinc finger DHHC-type palmitoyltransferase 17
  zinc finger protein 598, E3 ubiquitin ligase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.