TGFBI, transforming growth factor beta induced

TGFBI, transforming growth factor beta induced

• This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]

• Gene Synonyms (transforming growth factor-beta-induced protein ig-h3, RGD-CAP, RGD-containing collagen-associated protein, beta ig-h3, betaig-h3, kerato-epithelin, transforming growth factor beta-induced 68kDa, transforming growth factor, beta-induced, 68kD, BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, LCD1,)
• NCBI Gene ID: 7045
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15582
  UNIPROT ID#>>A0A0S2Z4Q2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transforming growth factor beta induced interacts with:

• family with sequence similarity 9 member B

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