SSX2B, SSX family member 2B

SSX2B, SSX family member 2B

• The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 6757, located about 45 kb upstream in the opposite orientation on chromosome X. [provided by RefSeq, Jul 2013]

• Gene Synonyms (CT5.2, CT5.2b, HOM-MEL-40, SSX, protein SSX2, cancer/testis antigen 5.2, cancer/testis antigen family 5, member 2b, synovial sarcoma, X breakpoint 2B, tumor antigen HOM-MEL-40,)
• NCBI Gene ID: 727837
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q16385
  UNIPROT ID#>>R9QTR3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SSX family member 2B interacts with:

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