PXDN, peroxidasin

PXDN, peroxidasin

• This gene encodes a heme-containing peroxidase that is secreted into the extracellular matrix. It is involved in extracellular matrix formation, and may function in the physiological and pathological fibrogenic response in fibrotic kidney. Mutations in this gene cause corneal opacification and other ocular anomalies, and also microphthalmia and anterior segment dysgenesis. [provided by RefSeq, Aug 2014]

• Gene Synonyms (peroxidasin homolog, melanoma-associated antigen MG50, p53-responsive gene 2 protein, vascular peroxidase 1, ASGD7, COPOA, D2S448, D2S448E, MG50, PRG2, PXN, VPO,)
• NCBI Gene ID: 7837
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92626
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

peroxidasin interacts with:

• ADP dependent glucokinase
  BCL2 interacting protein like
  canopy FGF signaling regulator 3
  CD96 molecule
  endoplasmic reticulum protein 44
  F-box protein 6
  HAUS augmin like complex subunit 1
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  insulin like 5
  limb development membrane protein 1 like
  phospholipase A2 group XIIA
  scavenger receptor class A member 3
  TNF receptor associated factor 4
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.