ALMS1, ALMS1 centrosome and basal body associated protein

ALMS1, ALMS1 centrosome and basal body associated protein

• This gene encodes a protein containing a large tandem-repeat domain as well as additional low complexity regions. The encoded protein functions in microtubule organization, particularly in the formation and maintanance of cilia. Mutations in this gene cause Alstrom syndrome. There is a pseudogene for this gene located adjacent in the same region of chromosome 2. Alternative splice variants have been described but their full length nature has not been determined. [provided by RefSeq, Apr 2014]

• Gene Synonyms (Alstrom syndrome protein 1, Alstrom syndrome 1, ALSS,)
• NCBI Gene ID: 7840
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8TCU4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ALMS1 centrosome and basal body associated protein interacts with:

• advillin
  alanyl-tRNA synthetase domain containing 1
  angiomotin
  Bardet-Biedl syndrome 7
  beta-transducin repeat containing E3 ubiquitin protein ligase
  BICD cargo adaptor 2
  cell division cycle 16
  centrobin, centriole duplication and spindle assembly protein
  centromere protein J
  centrosomal protein 104
  centrosomal protein 120
  centrosomal protein 128
  centrosomal protein 135
  centrosomal protein 152
  centrosomal protein 192
  centrosomal protein 63
  centrosomal protein 97
  chromosome 6 open reading frame 141
  crystallin lambda 1
  dickkopf WNT signaling pathway inhibitor 3
  differentially expressed in FDCP 8 homolog
  dynamin 3
  dystrobrevin binding protein 1
  G protein-coupled receptor associated sorting protein 2
  gigaxonin
  GTF2I repeat domain containing 1
  heat shock protein family B (small) member 8
  hook microtubule tethering protein 3
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  KIAA0753
  laccase domain containing 1
  large tumor suppressor kinase 2
  mediator complex subunit 4
  multiple EGF like domains 10
  MUS81 structure-specific endonuclease subunit
  ninein
  ninein like
  non-SMC condensin II complex subunit H2
  POC5 centriolar protein
  polo like kinase 4
  RAB, member of RAS oncogene family like 2A
  SAS-6 centriolar assembly protein
  src kinase associated phosphoprotein 1
  SUZ12 polycomb repressive complex 2 subunit
  thrombospondin type 1 domain containing 4
  transcription factor Dp family member 3
  valosin containing protein (p97)/p47 complex interacting protein 1
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.