ZNF426, zinc finger protein 426

ZNF426, zinc finger protein 426

• Kaposi's sarcoma-associated herpesvirus (KSHV) can be reactivated from latency by the viral protein RTA. The protein encoded by this gene is a zinc finger transcriptional repressor that interacts with RTA to modulate RTA-mediated reactivation of KSHV. While the encoded protein can repress KSHV reactivation, RTA can induce degradation of this protein through the ubiquitin-proteasome pathway to overcome the repression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

• Gene Synonyms (zinc finger protein 426, CTC-543D15.7, KSHV RTA binding protein, K-RBP,)
• NCBI Gene ID: 79088
• Species: Homo sapiens (Human)
• UNIPROT ID#>>K7ER43
  UNIPROT ID#>>Q9BUY5
  UNIPROT ID#>>Q59EH4
  UNIPROT ID#>>K7EME3
  UNIPROT ID#>>A0A024R7D7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

zinc finger protein 426 interacts with:

• armadillo repeat containing 7
  ATP synthase mitochondrial F1 complex assembly factor 2
  calcium and integrin binding family member 3
  centrosomal protein 70
  enkurin domain containing 1
  FAM161 centrosomal protein A
  gasdermin D
  HEXIM P-TEFb complex subunit 2
  keratin associated protein 4-12
  leucine zipper tumor suppressor 2
  ligand of numb-protein X 1
  LON peptidase N-terminal domain and ring finger 1
  mitochondrial assembly of ribosomal large subunit 1
  N-acetyltransferase domain containing 1
  tektin 4
  testis specific 10
  zinc finger and SCAN domain containing 23
  zinc finger CCCH-type and G-patch domain containing

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.