MTERF1, mitochondrial transcription termination factor 1

MTERF1, mitochondrial transcription termination factor 1

• This gene encodes a mitochondrial transcription termination factor. This protein participates in attenuating transcription from the mitochondrial genome; this attenuation allows higher levels of expression of 16S ribosomal RNA relative to the tRNA gene downstream. The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding. There is evidence that, for this protein, the zippers participate in intramolecular interactions that establish the three-dimensional structure required for DNA binding. [provided by RefSeq, Jul 2008]

• Gene Synonyms (transcription termination factor 1, mitochondrial, transcription termination factor, mitochondrial, MTERF,)
• NCBI Gene ID: 7978
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q99551
  UNIPROT ID#>>B4DPR9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mitochondrial transcription termination factor 1 interacts with:

• DnaJ heat shock protein family (Hsp40) member C21
  exocyst complex component 6B
  pyridoxamine 5'-phosphate oxidase
  synaptotagmin like 2
  transmembrane protein 128
  tropomodulin 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.