TLCD3A, TLC domain containing 3A

TLCD3A, TLC domain containing 3A

• The protein encoded by this gene is a membrane-associated protein that promotes lung carcinogenesis. The encoded protein may be involved in amino acid transport and glutathione metabolism since it can interact with a solute carrier family member (SLC3A2) and an isoform of gamma-glutamyltranspeptidase-like 3. An alternatively spliced variant encoding a protein that lacks a 32 aa internal segment showed the opposite effect, inhibiting lung cancer cell growth. Knockdown of this gene also inhibited lung carcinogenesis and tumor cell growth. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

• Gene Synonyms (TLC domain-containing protein 3A, family with sequence similarity 57 member A, membrane protein expressed in epithelial-like lung adenocarcinoma, protein FAM57A, CT120, FAM57A,)
• NCBI Gene ID: 79850
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8TBR7
  UNIPROT ID#>>I3L336
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TLC domain containing 3A interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.