NR4A3, nuclear receptor subfamily 4 group A member 3

NR4A3, nuclear receptor subfamily 4 group A member 3

• This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

• Gene Synonyms (nuclear receptor subfamily 4 group A member 3, chondrosarcoma, extraskeletal myxoid, fused to EWS, mitogen-induced nuclear orphan receptor, neuron-derived orphan receptor 1, nuclear hormone receptor NOR-1, translocated in extraskeletal chondrosarcoma, CHN, CSMF, MINOR, NOR1, TEC,)
• NCBI Gene ID: 8013
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92570
  UNIPROT ID#>>A0A024R168
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nuclear receptor subfamily 4 group A member 3 interacts with:

• ADAMTS like 4
  chordin
  COP9 signalosome subunit 5
  cysteine rich tail 1
  hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
  keratin associated protein 10-1
  keratin associated protein 10-5
  keratin associated protein 10-8
  keratin associated protein 12-3
  keratin associated protein 12-4
  keratin associated protein 4-11
  keratin associated protein 4-2
  keratin associated protein 4-4
  keratin associated protein 5-11
  keratin associated protein 5-3
  keratin associated protein 5-6
  keratin associated protein 6-3
  keratin associated protein 9-2
  keratin associated protein 9-3
  keratin associated protein 9-8
  keratinocyte proline rich protein
  late cornified envelope 2B
  late cornified envelope 2D
  lysine demethylase 5B
  macoilin 1
  reversion inducing cysteine rich protein with kazal motifs
  SPARC related modular calcium binding 1
  tripartite motif containing 28
  vasorin
  vir like m6A methyltransferase associated
  von Willebrand factor C domain containing 2 like
  zinc finger protein 330

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.