ARMC10, armadillo repeat containing 10

ARMC10, armadillo repeat containing 10

• This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011]

• Gene Synonyms (armadillo repeat-containing protein 10, specific splicing variant involved in hepatocarcinogenesis, splicing variant involved in hepatocarcinogenesis protein, PNAS-112, PNAS112, PSEC0198, SVH,)
• NCBI Gene ID: 83787
• Species: Homo sapiens (Human)
• UNIPROT ID#>>H7BXQ8
  UNIPROT ID#>>Q8N2F6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

armadillo repeat containing 10 interacts with:

• calpain small subunit 2
  family with sequence similarity 25 member A
  family with sequence similarity 25 member C
  family with sequence similarity 25 member G

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.