HIRIP3, HIRA interacting protein 3

HIRIP3, HIRA interacting protein 3

• The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Aug 2011]

• Gene Synonyms (HIRA-interacting protein 3,)
• NCBI Gene ID: 8479
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BW71
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

HIRA interacting protein 3 interacts with:

• ATP binding cassette subfamily F member 3
  exportin 7
  Fas associated factor 1
  heat shock protein family H (Hsp110) member 1
  IQ motif containing B1
  poly(U) binding splicing factor 60
  protein arginine methyltransferase 3
  RAD18 E3 ubiquitin protein ligase
  RAN binding protein 3
  Sec23 homolog A, COPII coat complex component
  serum/glucocorticoid regulated kinase 2
  WW domain containing oxidoreductase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.