KLF7, Kruppel like factor 7

KLF7, Kruppel like factor 7

• The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

• Gene Synonyms (Krueppel-like factor 7, Kruppel-like factor 7 (ubiquitous), ubiquitous Kruppel-like factor, ubiquitous Kruppel-like transcription factor, UKLF,)
• NCBI Gene ID: 8609
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75840
  UNIPROT ID#>>A0A024R3X8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Kruppel like factor 7 interacts with:

• F-box protein 38

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.