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- Sequence Verification
IL18RAP, interleukin 18 receptor accessory protein
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The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
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Gene Synonyms (interleukin-18 receptor accessory protein, CD218 antigen-like family member B, IL-18 receptor accessory protein, IL-18 receptor beta, cluster of differentiation w218b, interleukin-1 receptor 7, interleukin-18 receptor beta, ACPL, CD218b, CDw218b, IL-18R-beta, IL-18RAcP, IL-18Rbeta, IL-1R-7, IL-1R7, IL-1RAcPL, IL18RB,)
- NCBI Gene ID:
8807
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>O95256
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for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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interleukin 18 receptor accessory protein interacts with:
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