ALKBH1, alkB homolog 1, histone H2A dioxygenase

ALKBH1, alkB homolog 1, histone H2A dioxygenase

• This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. [provided by RefSeq, Jul 2008]

• Gene Synonyms (nucleic acid dioxygenase ALKBH1, DNA 6mA demethylase, DNA N6-methyl adenine demethylase, DNA N6-methyl adenine demethylase ALKBH1, DNA demethylase ALKBH1, DNA lyase ABH1, DNA oxidative demethylase ALKBH1, alkB, alkylation repair homolog 1, alkylated DNA repair protein alkB homolog 1, alkylation repair, alkB homolog, alpha-ketoglutarate-dependent dioxygenase ABH1, mRNA N(3)-methylcytidine demethylase, tRNA N1-methyl adenine demethylase, ABH, ABH1, ALKBH, alkB, hABH,)
• NCBI Gene ID: 8846
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5XKL0
  UNIPROT ID#>>Q13686
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

alkB homolog 1, histone H2A dioxygenase interacts with:

• DnaJ heat shock protein family (Hsp40) member B6
  proteasome 26S subunit, non-ATPase 14

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.