- Gene Overview
- Interaction Network
- Sequence Verification
ST3GAL5, ST3 beta-galactoside alpha-2,3-sialyltransferase 5
-
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
-
Gene Synonyms (lactosylceramide alpha-2,3-sialyltransferase, CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase, ST3 beta-galactoside alpha-23-sialyltransferase 5, alpha 2,3-sialyltransferase V, ganglioside GM3 synthase, sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase), SATI, SIAT9, SIATGM3S, SPDRS, ST3Gal V, ST3GalV,)
- NCBI Gene ID:
8869
- Species:
Homo sapiens (Human)
-
UNIPROT ID#>>A0A0S2Z4Q7
UNIPROT ID#>>Q9UNP4
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
ST3 beta-galactoside alpha-2,3-sialyltransferase 5 interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
|