SLC25A14, solute carrier family 25 member 14

SLC25A14, solute carrier family 25 member 14

• Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Uncoupling proteins separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. Uncoupling proteins facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 4. [provided by RefSeq, Aug 2013]

• Gene Synonyms (brain mitochondrial carrier protein 1, mitochondrial uncoupling protein 5, BMCP1, UCP5,)
• NCBI Gene ID: 9016
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O95258
  UNIPROT ID#>>F6SL11
  UNIPROT ID#>>B4DMK1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

solute carrier family 25 member 14 interacts with:

• butyrophilin subfamily 2 member A1
  lysosomal associated membrane protein 3
  mucin 20, cell surface associated
  pleckstrin homology domain containing A4
  RNA polymerase III subunit E
  torsin 1A interacting protein 2
  V-set and immunoglobulin domain containing 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.