PIGQ, phosphatidylinositol glycan anchor biosynthesis class Q

PIGQ, phosphatidylinositol glycan anchor biosynthesis class Q

• This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]

• Gene Synonyms (phosphatidylinositol N-acetylglucosaminyltransferase subunit Q, N-acetylglucosaminyl transferase component Gpi1, N-acetylglucosamyl transferase component GPI1, PIG-Q, c407A10.1 (GPI1 (N-acetylglucosaminyl transferase component)), phosphatidylinositol glycan, class Q, phosphatidylinositol-glycan biosynthesis class Q protein, EIEE77, GPI1, c407A10.1,)
• NCBI Gene ID: 9091
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BRB3
  UNIPROT ID#>>B2RAU6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphatidylinositol glycan anchor biosynthesis class Q interacts with:

• glycerophosphodiester phosphodiesterase domain containing 5
  interleukin 17 receptor B
  interleukin 17 receptor C
  phosphatidylinositol glycan anchor biosynthesis class P
  protocadherin alpha subfamily C, 2
  tectonic family member 2
  TNF superfamily member 13b
  transmembrane and coiled-coil domains 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.