PIWIL1, piwi like RNA-mediated gene silencing 1

PIWIL1, piwi like RNA-mediated gene silencing 1

• This gene encodes a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

• Gene Synonyms (piwi-like protein 1, piwi homolog, CT80.1, HIWI, MIWI, PIWI,)
• NCBI Gene ID: 9271
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96J94
  UNIPROT ID#>>A0A024RBS5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

piwi like RNA-mediated gene silencing 1 interacts with:

• dicer 1, ribonuclease III
  tubulin alpha 1b
  tubulin beta 3 class III

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.