HMGN3, high mobility group nucleosomal binding domain 3

HMGN3, high mobility group nucleosomal binding domain 3

• The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is a related pseudogene on chromosome 1. [provided by RefSeq, Jan 2016]

• Gene Synonyms (high mobility group nucleosome-binding domain-containing protein 3, TR-interacting protein 7, thyroid hormone receptor interacting protein 7, PNAS-24, PNAS-25, TRIP7,)
• NCBI Gene ID: 9324
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15651
  UNIPROT ID#>>A0A087WZE9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

high mobility group nucleosomal binding domain 3 interacts with:

• casein kinase 1, delta
  ninein
  TERF2 interacting protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.