XAGE2, X antigen family member 2

XAGE2, X antigen family member 2

• This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in normal testis, and in Ewing's sarcoma, rhabdomyosarcoma, a breast cancer and a germ cell tumor. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. [provided by RefSeq, Jul 2008]

• Gene Synonyms (X antigen family member 2, G antigen family D member 3, X antigen family, member 2B, cancer/testis antigen 12.2, cancer/testis antigen family 12, member 2, CT12.2, GAGED3, XAGE-2, XAGE2B,)
• NCBI Gene ID: 9502
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96GT9
  UNIPROT ID#>>A0A024R2A6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

X antigen family member 2 interacts with:

• chromobox 5
  euchromatic histone lysine methyltransferase 1
  euchromatic histone lysine methyltransferase 2
  forkhead box P4
  germ cell-less 1, spermatogenesis associated
  germ cell-less 2, spermatogenesis associated
  protection of telomeres 1
  TERF2 interacting protein
  WIZ zinc finger
  zinc finger protein 644

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.