MLEC, malectin

MLEC, malectin

• This gene encodes the carbohydrate-binding protein malectin which is a Type I membrane-anchored endoplasmic reticulum protein. This protein has an affinity for Glc2Man9GlcNAc2 (G2M9) N-glycans and is involved in regulating glycosylation in the endoplasmic reticulum. This protein has also been shown to interact with ribophorin I and may be involved in the directing the degradation of misfolded proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

• Gene Synonyms (malectin, oligosaccharyltransferase complex subunit (non-catalytic), KIAA0152,)
• NCBI Gene ID: 9761
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14165
  UNIPROT ID#>>F5GX14
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

malectin interacts with:

• anterior gradient 2, protein disulphide isomerase family member
  centrosomal protein 152
  cytochrome b5 type B
  dynactin 3
  golgi transport 1B
  HECT domain E3 ubiquitin protein ligase 1
  neural precursor cell expressed, developmentally down-regulated gene 1
  pleckstrin homology domain containing A4
  RNA binding motif protein 8A
  sodium channel and clathrin linker 1
  solute carrier family 15 member 3
  STT3 oligosaccharyltransferase complex catalytic subunit B
  tectonic family member 1
  tectonic family member 2
  tectonic family member 3
  thyroid hormone receptor interactor 11
  transmembrane p24 trafficking protein 2
  transmembrane protein 41B
  unc-93 homolog B1, TLR signaling regulator
  vir like m6A methyltransferase associated
  WW domain containing oxidoreductase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.