AP5Z1, adaptor related protein complex 5 subunit zeta 1

AP5Z1, adaptor related protein complex 5 subunit zeta 1

• This gene was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase (PMID:20613862). [provided by RefSeq, Jan 2011]

• Gene Synonyms (AP-5 complex subunit zeta-1, adapter-related protein complex 5 zeta subunit, adaptor related protein complex 5 zeta 1 subunit, adaptor-related protein complex 5 zeta subunit, zeta5, KIAA0415, SPG48, zeta,)
• NCBI Gene ID: 9907
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43299
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

adaptor related protein complex 5 subunit zeta 1 interacts with:

• forkhead box K1
  LY6/PLAUR domain containing 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.