CD99, CD99 molecule (Xg blood group)

CD99, CD99 molecule (Xg blood group)

• The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016]

• Gene Synonyms (HBA71, MIC2, MIC2X, MIC2Y, MSK5X, CD99 antigen, E2 antigen, MIC2 (monoclonal antibody 12E7), T-cell surface glycoprotein E2, antigen identified by monoclonal 12E7, Y homolog, antigen identified by monoclonal antibodies 12E7, F21 and O13, cell surface antigen 12E7, cell surface antigen HBA-71, cell surface antigen O13, surface antigen MIC2,)
• NCBI Gene ID: 4267
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P14209
  UNIPROT ID#>>A0A096LP69
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CD99 molecule (Xg blood group) interacts with:

• endosome associated trafficking regulator 1
  melatonin receptor 1A
  melatonin receptor 1B
  peptidylprolyl isomerase A
  ribosomal protein S6 kinase A2
  small glutamine rich tetratricopeptide repeat containing alpha
  thyroid hormone receptor interactor 13
  transmembrane protein 17
  transmembrane protein 216
  ubiquilin 1
  ubiquilin 4
  ubiquitin conjugating enzyme E2 H

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.