NR4A2, nuclear receptor subfamily 4 group A member 2

NR4A2, nuclear receptor subfamily 4 group A member 2

• This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

• Gene Synonyms (HZF-3, NOT, NURR1, RNR1, TINUR, nuclear receptor subfamily 4 group A member 2, NGFI-B/nur77 beta-type transcription factor homolog, T-cell nuclear receptor NOT, immediate-early response protein NOT, intermediate-early receptor protein, nuclear receptor related 1, nur related protein-1, human homolog of, orphan nuclear receptor NR4A2, orphan nuclear receptor NURR1, transcriptionally inducible nuclear receptor related 1, transcriptionally-inducible nuclear receptor,)
• NCBI Gene ID: 4929
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P43354
  UNIPROT ID#>>F1D8N6
  UNIPROT ID#>>F1DAL2
  UNIPROT ID#>>Q53EL4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nuclear receptor subfamily 4 group A member 2 interacts with:

• armadillo repeat containing 4
  bromodomain adjacent to zinc finger domain 1B
  COP9 signalosome subunit 5
  nuclear receptor coactivator 1
  nuclear receptor corepressor 2
  peroxisome proliferator activated receptor gamma
  PPARG coactivator 1 alpha
  protein inhibitor of activated STAT 4
  retinoid X receptor alpha
  retinoid X receptor beta
  ribosomal protein S6 kinase A1
  SIN3 transcription regulator family member A
  splicing factor proline and glutamine rich
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  transcription elongation factor A like 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.