PSMD10, proteasome 26S subunit, non-ATPase 10

PSMD10, proteasome 26S subunit, non-ATPase 10

• This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.[provided by RefSeq, Mar 2011]

• Gene Synonyms (26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit p28, ankyrin repeat protein, gankyrin, hepatocellular carcinoma-associated protein p28-II, proteasome (prosome, macropain) 26S subunit, non-ATPase, 10, dJ889N15.2, p28, p28(GANK),)
• NCBI Gene ID: 5716
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75832
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

proteasome 26S subunit, non-ATPase 10 interacts with:

• adhesion regulating molecule 1
  autophagy and beclin 1 regulator 1
  autophagy related 12
  autophagy related 5
  autophagy related 7
  beclin 1
  coiled-coil domain containing 74B
  coiled-coil domain containing 92
  CUGBP Elav-like family member 1
  dimethylarginine dimethylaminohydrolase 1
  docking protein 2
  dual specificity phosphatase 12
  ELOVL fatty acid elongase 1
  H2B clustered histone 4
  hypoxia inducible factor 1 subunit alpha inhibitor
  kelch like ECH associated protein 1
  LIM domain binding 1
  mediator complex subunit 20
  mediator complex subunit 23
  NCK adaptor protein 2
  O-acyl-ADP-ribose deacylase 1
  phosphoserine aminotransferase 1
  pleckstrin homology domain containing A4
  proteasomal ATPase associated factor 1
  proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
  proteasome 26S subunit, non-ATPase 11
  proteasome 26S subunit, non-ATPase 12
  proteasome 26S subunit, non-ATPase 13
  proteasome 26S subunit, non-ATPase 14
  proteasome 26S subunit, non-ATPase 6
  protein tyrosine phosphatase non-receptor type 2
  RB transcriptional corepressor 1
  RELA proto-oncogene, NF-kB subunit
  ring finger protein 11
  SEM1 26S proteasome complex subunit
  sequestosome 1
  small nuclear ribonucleoprotein polypeptide B2
  tripartite motif containing 14
  tumor protein p53
  ubiquitin C
  ubiquitin C-terminal hydrolase L5
  ubiquitin like domain containing CTD phosphatase 1
  ubiquitin protein ligase E3A
  ubiquitin specific peptidase 14
  WW domain containing E3 ubiquitin protein ligase 2
  zinc finger AN1-type containing 2B
  zw10 kinetochore protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.